Jan 2025: Congratulations to Dr. Martynas Sirvinskas

Congratulations to Dr. Martynas Sirvinskas for defending his thesis titled The Preparation of Novel Organoboranes and Mastering the Four Elements of Peptide Chemistry: Discovery, Synthesis, Physiochemical Analysis and Structural Control!

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Aug 2024: Award Announcement

Congratulations to Andrei for receiving the American Chemistry Society Author C. Cope Scholar Award! This award recognizes outstanding achievements in the field of organic chemistry, with significant impact made within the last five years!


Aug 2024: New Publication

Congratulations to Martynas and George for the publication of their work on Stabilization of 3,10-Helices in Macrocycles Using Dominant Rotor Methodology in the Journal of the American Chemistry Society!

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Aug 2024: New Publication

Congratulations to Alina, Matthew and Chelsey for the publication of their work on Terpenoid Cyclophanes with Planar Chirality in the Journal of the American Chemistry Society!

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Aug 2024: Congratulations to Dr. Alina Trofimova

Congratulations to Dr. Alina Trofimova for defending her thesis titled Boron-Based Compounds in the Synthesis of Small Molecules, Heterocycles, and Strained Cyclophanes!

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March 2024: New Publication

Congratulations to Solomon and Nicholas for the publication of their work on Identification of "Structural Pin" Interactions and Their Significance for the Conformational Control of Macrocyclic Scaffolds published in Angewandte Chemie!

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January 2024: New Publication

Congratulations to Alina for the publication of her work on A Boron Scan of Ethyl Acetoacetate Leads to Versatile Building Blocks in Angewandte Chemie!

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January 2024: Congratulations to Dr. Vincent Trudel!

Congratulations to Dr. Vincent Trudel for defending his thesis titled Synthesis and Applications of Aminoboronic Acids!

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January 2024: New Publication

Congratulations to Alina for the publication of her work on An Exploration of Regioselectivity During Formation of Amino-boronates from Epoxides in Synlett!

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January 2024: New Publication

Congratulations to Diego for the publication of his work on The Role of Attractive Non-Covalent Interactions in Peptide Macrocyclization in the Journal of Organic Chemistry!

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October 2023: New Publication

Congratulations to Alina and Chelsey for the publication of their work on Boryl Acrylaldehyde: An Elusive Member of the α-Boryl Aldehyde Class of Reagent in Synlett!

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September 2023: Congratulations to Nicholas

Congratulations to Nicholas for the completion of his M. Sc. thesis titled The Role of Conformation Bias in the Atropselective Macrocyclization of Linear Peptides!


September 2023: Welcome New Graduate Students

Welcome to the Yudin lab Morgan (B. Sc. University of Waterloo) and Betty (B. Sc. UBC Vancouver)!

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August 2023: New Publication

Congratulations to Matthew and Nicholas for the publication of their work on Nitrilium Ion Trapping as a Strategy to Access Structurally Diverse Heterobiaryl-Containing Peptide Macrocycles in Chemical Science


March 2023: New Publication

Congratulations to Alina for the publication of our collaboration with the Honggen Wang group (Sun Yat-Sen University) on β-Boron Effect Enables Regioselective and Stereospecific Electrophilic Addition to Alkenes in JACS!

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December 2022: Congratulations to Dr. Chirag Apte!

Congratulations to Dr. Chirag Apte for defending his thesis titled Reaction discovery through functional small molecules: From peptides to fluorophores! Chirag will be starting a position as Research Scientist at X-Chem in Montréal.


November 2022: New Publication

Congratulations to Sean and George for the publication of their work on Single Atom Ring Contraction of Peptide Macrocycles Using Cornforth Rearrangement in Angewandte Chemie! The publication has received the designation of "Very Important Paper".

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October 2022: New Publication

Congratulations to Tien for the publication of his work on Iminologous Epoxide Ring-Closure in Chemical Science!

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October 2022: Congratulations to Dr. Sean Huh!

Congratulations to Dr. Sean Huh for defending his PhD thesis titled Modification of Macrocyclic Backbone to Control Conformation and Reactivity! Sean will be starting a position as Scientist I at Paraza Pharma.


September 2021: Congratulations to Dr. Chieh-Hung Tien!

Congratulations to Dr. Chieh-Hung Tien for defending his PhD thesis titled "Carbonyl Functional Groups in Reaction Development: Carbonylative Cross-Coupling, α-Hydrazination, and C-C Cleavage" !


June 2022: New article

Congratulations to George for the publication of his work on Property-Driven Development of Passively Permeable Macrocyclic Scaffolds Using Heterocycles in Angewandte Chemie!

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June 2022: New research account

Andrei's most recent research account on the topic of Synthetic tools that enable synthesis and understanding of bioactive macrocycles has been published in Synlett!

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April 2022: New publication

Congratulations to Timothy, Diego, George and Fiona for the publication of their work on Navigating complex peptide structures using macrocycle conformational maps in RSC Chemical Biology!

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March 2022: New publication

Congratulations to Vincent, Chelsey and Joanne for the publication of the work "Towards depeptidized aminoboronic acid derivatives through the use of borylated iminium ions" in Chemical Communications as part of a themed collection on Boron Chemistry in the 21st Century: From Synthetic Curiosities to Functional Molecules!

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January 2022: Welcome to Frauke!

We are fortunate to welcome Frauke Weidlich from Armido Studer's lab at the University of Muenster!

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December 2021: New publication

Congratulations to Harry, Diego and our collaborators from the Tantillo and Schofield labs for the publication of their recent work on the Synthesis and Application of Constrained Amidoboronic Acids Using Amphoteric Boron-Containing Building Blocks in the Journal of Organic Chemistry!

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November 2021: Congratulations to Tim!

Congratulations to Tim for the completion of his M.Sc. thesis titled: Conformational Analysis of Rotationally Restricted Macrocyclic Peptides !


September 2021: Welcome to new students

A very warm welcome to our lab's first year graduate students Chelsey (B.Sc. UBC Okanagan), Nick (B.Sc. McMaster University), and Matthew (B.Sc. and M.Sc. University of Waterloo)!

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August 2021: New Review

Congratulations to Vincent, Tien and Alina for the publication of their review on the toic of Interruted reactions in chemical synthesis in Nature Reviews Chemistry!

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July 2021: New Publication

Congratulations to Tien, Alina the Synthesis of Borylated Hydrazino Acid Derivatives in the Synthesis special issue dedicated to Prof. Sarah Reisman!

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July 2021: New Publication

Congratulations to Harry, Diego and Katherine on the recent publication of their work on the Synthesis of Fluorinated Aminoalkylboronic Acids from Amphoteric α-Boryl Aldehydes in Angewandte Chemie!

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April 2021: New Publication

Congratulations to Alina, Aleksandra, Tien and Martynas for the publication of their work on Acylboronates in Polarity-Reversed Generation of Acyl Palladium(II) Intermediates in Organic Letters!

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April 2021: JACS Spotlight

Our most recent JACS article has been highlighted in [Spotlights on Recent JACS Publications]()!

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March 2021: New Publication

Congratulations to Shinya, Sean and Solomon for their publication on Two-Dimensional Barriers for Probing Conformational Shifts in Macrocycles in J. Am. Chem. Soc.!

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March 2021: New Perspective

Congratulations to Aleks and Chirag for the publication of their perspective on Acyl Metalloids: Conformity and Deviation from Carbonyl Reactivity in Chemical Science!

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March 2021: Nature Chemistry cover

Our most recent Nature Chemistry manuscript was featured as the cover for the March issue! A big thank you to artist Ella Marushchenko

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February 2021: New Publication

Congratulations to Diego, Solomon, Anastasia, Yury, Timothy and Gabe for the publication of their work on Illuminating the dark conformational space of macrocycles using dominant rotors in Nature Chemistry!

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February 2021: Chemistry World article

Andrei's invited opinion article on Space, energy and synthetic half-reactions has been published in Chemistry World!

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February 2021: Welcome to George

We wish to welcome our new postdoctoral fellow [George Saunders]() (PhD University of Warwick)!

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January 2021: New Publication

Congratulations to Sherif, Tien, Stephanie, Marty and collaborators for their most recent publication on Oxidative Rearrangement of MIDA (N-Methyliminodiacetic Acid) Boronates: Mechanistic Insights and Synthetic Applications!

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November 2020: New Publication

Congratulations to Sean and Solomon for the publication of their work on Amidine Functionality As a Conformational Probe of Cyclic Peptides!

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October 2020: New publication

Congratulations to Tien, Alina and Aleks for the publication of the work on Carboxyboronate as a Versatile in situ CO surrogate in Palladium-Catalyzed Carbonylative Transformations!

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September 2020: Welcome to new student

Welcome to our new graduate student [Alaeddeen Al-Toum]() (McMaster University)!

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September 2020: New publication

Have a look at Andrei's perspective article on Synthetic Half-Reactions, out in Chemical Science!

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September 2020: New publication

Have a look at Frank, Tien and Shinya A.'s publication on the Synthesis of α-Bromoacetyl MIDA Boronate in Organic Syntheses!

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September 2020: Award announcement

Congratulations to our summer undergraduate NSERC student Seamus Corlett for earning an award at the department's annual summer poster session!


August 2020: Congratulations to Dr. Aleksandra Holownia for defending her PhD thesis!

The title of her thesis is “Investigating the Synthesis and Reactivity of Boron Carbonyl Compounds”.Aleksandra will joining the Process Chemistry group at AbbVie in Chicago!


August 2020: Dr. Diego Diaz wins Chair's Gold Medal

Please join us in congratulating Diego (PhD '19) for winning the 2020 Chair's Gold Medal! The title of his thesis is Identification of novel structural motifs for mining the conformational space of boron- and peptide-based molecules.


August 2020: Canada Research Chair Appointment

Congratulations to Andrei on his recent appointment as a Tier 1 Canada Research Chair in Medicine by Design! "This CRC funding will allow my lab to understand how to force a wide range of chemical structures into unusual, yet stable, conformations," says Yudin. "We will apply the knowledge of the emerging dark space in our effort to generate new bioactive forms of chemical structures and understand how they interact with proteins and other biomolecules."


July 2020: New Publication

Check out Chirag, Diego and Timur's work on Grafting bis(heterocycle) motifs into ring structures!

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July 2020: New Publication

Check out Yury and Chirag's work on fluorescent boramidines in collaboration with the Seferos and Aspuru-Guzik group!


June 2020: New essay

Check out Andrei's essay on discoverability in science posted on ChemRxiv


January 2020: Congratulations to Dr. Joanne Tan for successfully defending her PhD thesis!


December 2019: Congratulations to Dr. Diego Diaz for successfully defending his PhD thesis!

Diego is pursuing research as an NSERC postdoctoral fellow in the lab of Professor Eric Jacobsen at Harvard University


December 2019: Congratulations to Dr. Sherif Kaldas for successfully defending his PhD thesis!

Sherif will be pursuing as postdoctoral fellow at RWTH Aachen University with Prof. Franziska Schoenebeck


September 2019: Welcome to new students

Welcome to our new graduate students Alina (University of Toronto), Martynas (University of Toronto Mississauga) and Timothy (University of Guelph) as well as our new visiting student Fiona (Johannes Gutenberg-University Mainz)!


August 2019: New Review

Check out Solomon, Sean and Diego's recent Focus Review on Conformational Control of Macrocycles by Remote Structural Modification!

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August 2019: New Paper

Check out Aleks and Tien's work on carboxy-MIDA-boronate, a new versatile C1 building block!

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August 2019: New Paper

Check out Aki and Sherif's recent work on using the Petasis borono-Mannich reaction to access conformationnaly stable peptide macrocycles!

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June 2019: New paper

Check out Joanne's new paper on boron-based peptidomimetics inhibitors!

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April 2019: Killam Research Fellowship Prize

Congratulations to Andrei for being awarded a Killam Research Fellowship Prize!


April 2019: R.U. Lemieux Award

Congratulations to Andrei for winning the 2019 R.U. Lemieux Award!


December 2018: Chemical Science

From December 1 2018, Andrei will serve as an Associate Editor of Chemical Science.


December 2018: New Review

Check out Joanne’s review on borylated reagents for multicomponent processes!


Older announcements

To view older announcements, follow this link.