November 17, 2025:
Congratulations to Kane, Caleb, Betty, Morgan and Daniel for the publication of their work on Frame-Shifted Synthesis of Oligoheterocycles as a Platform for Molecular Design in Angewandte Chemie International Edition!
November 26, 2025:
Congratulations to Morgan for the publication of his work on Isoactivity in Chemistry in Chem!
October 21st, 2025:
Congratulations to Matt, Kane, Daniel and Betty for the publication of their work on A Three-Component Path to Amino Thiadiazoles and Amino Oxadiazoles via a Nitrilium Ylide in The Journal of Organic Chemistry!
September 15th, 2025:
Congratulations to Chirag, Nick and Betty for the publication of their work on A borindolizine platform for the design of fluorophores with tunable emissions in Chemical Science!
September 1st, 2025:
Welcome to the Yudin lab Jelena (B. Sc. University of Toronto) and Logan (B. Sc. University of Guelph) who are joining us as graduate students! We also want to extend a warm welcome to new undergraduate students Thomas S. (UofT), Thomas R. (UofT), Chole (UofT) and Chris (UofT)!
July 21st, 2025:
Congratulations to Dr. Matthew Diamandas for the successful defense of his thesis!
April 25, 2025:
Congratulations to Matt, Daniel and Betty for the publication of their work on Pseudo-Ring Methodology to Control the Conformations of Macrocyclic Peptides in Chemistry -- A European Journal!
Welcome to the Yudin lab Sally (UofT), Devishi (U Waterloo), and Martina (UofT)!
Feb 5th, 2025:
Congratulations to Dr. Martynas Sirvinskas for defending his thesis titled The Preparation of Novel Organoboranes and Mastering the Four Elements of Peptide Chemistry: Discovery, Synthesis, Physiochemical Analysis and Structural Control!
Congratulations to Andrei for receiving the American Chemistry Society Author C. Cope Scholar Award! This award recognizes outstanding achievements in the field of organic chemistry, with significant impact made within the last five years!
Welcome to the Yudin lab Kane (Ph.D. University of St. Andrews, UK, M. Sc. Durham University, UK) who will be joining us as a postdoctoral fellow!
Aug 18th, 2024:
Congratulations to Martynas and George for the publication of their work on Stabilization of 3,10-Helices in Macrocycles Using Dominant Rotor Methodology in the Journal of the American Chemistry Society!
Aug 12th, 2024:
Congratulations to Alina, Matthew and Chelsey for the publication of their work on Terpenoid Cyclophanes with Planar Chirality in the Journal of the American Chemistry Society!
Aug 1st, 2024:
Congratulations to Dr. Alina Trofimova for defending her thesis titled Boron-Based Compounds in the Synthesis of Small Molecules, Heterocycles, and Strained Cyclophanes!
July 8th, 2024,
Congratulations to Solomon and Nicholas for the publication of their work on Identification of "Structural Pin" Interactions and Their Significance for the Conformational Control of Macrocyclic Scaffolds published in Angewandte Chemie International Edition!
Welcome to the Jelena and James!
April 8th, 2024:
Congratulations to Alina and Marty for the publication of her work on A Boron Scan of Ethyl Acetoacetate Leads to Versatile Building Blocks in Angewandte Chemie International Edition!
Welcome to the Yudin lab Chenchen (Ph.D. McGill University) who will be joining us as a postdoctoral fellow!
Jan 24th, 2024:
Congratulations to Dr. Vincent Trudel for defending his thesis titled Synthesis and Applications of Aminoboronic Acids!
Jan 11th, 2024:
Congratulations to Alina, Chelsey, Joanne and Vince for the publication of their work on An Exploration of Regioselectivity During Formation of Amino-boronates from Epoxides in Synlett!
Jan 13th, 2024:
Congratulations to Diego and George for the publication of their work on The Role of Attractive Non-Covalent Interactions in Peptide Macrocyclization in the Journal of Organic Chemistry!
Oct 12th, 2023:
Congratulations to Alina and Chelsey for the publication of their work on Boryl Acrylaldehyde: An Elusive Member of the α-Boryl Aldehyde Class of Reagent in Synlett!
Congratulations to Nicholas Heller for the completion of his M. Sc. thesis titled The Role of Conformation Bias in the Atropselective Macrocyclization of Linear Peptides!
Welcome to the Yudin lab Morgan (B. Sc. University of Waterloo) and Betty (B. Sc. UBC Vancouver) who are joining us as graduate students! We would also like to extend a warm welcome to Atang (UofT) who is joining us as an undergraduate!
Aug 9th, 2023:
Congratulations to Matthew and Nicholas for the publication of their work on Nitrilium Ion Trapping as a Strategy to Access Structurally Diverse Heterobiaryl-Containing Peptide Macrocycles in Chemical Science!
Welcome to the Yudin lab Caleb (Ph.D. University of Connecticut) who will be joining us as a postdoctoral fellow!
Congratulations to Alina for being award the Dean's Doctoral Excellence Scholarship!
March 22, 2023:
Congratulations to Alina for the publication of our collaboration with the Honggen Wang group (Sun Yat-Sen University) on β-Boron Effect Enables Regioselective and Stereospecific Electrophilic Addition to Alkenes in JACS!
Congratulations to Dr. Chirag Apte for defending his thesis titled Reaction discovery through functional small molecules: From peptides to fluorophores! Chirag will be starting a position as Research Scientist at X-Chem in Montréal!
Congratulations to Sean and George for the publication of their work on Single Atom Ring Contraction of Peptide Macrocycles Using Cornforth Rearrangement in Angewandte Chemie! The publication has received the designation of "Very Important Paper".
Congratulations to Tien for the publication of his work on Iminologous Epoxide Ring-Closure in Chemical Science!
Congratulations to Dr. Sean Huh for defending his PhD thesis titled Modification of Macrocyclic Backbone to Control Conformation and Reactivity! Sean will be starting a position as Scientist I at Paraza Pharma.
Congratulations to Dr. Chieh-Hung Tien for defending his PhD thesis titled Carbonyl Functional Groups in Reaction Development: Carbonylative Cross-Coupling, α-Hydrazination, and C-C Cleavage !
Congratulations to George for the publication of his work on Property-Driven Development of Passively Permeable Macrocyclic Scaffolds Using Heterocycles in Angewandte Chemie!
Andrei's most recent research account on the topic of Synthetic tools that enable synthesis and understanding of bioactive macrocycles has been published in Synlett!
Congratulations to Timothy, Diego, George and Fiona for the publication of their work on Navigating complex peptide structures using macrocycle conformational maps in RSC Chemical Biology!
Congratulations to Vincent, Chelsey and Joanne for the publication of the work Towards depeptidized aminoboronic acid derivatives through the use of borylated iminium ions in Chemical Communications as part of a themed collection on Boron Chemistry in the 21st Century: From Synthetic Curiosities to Functional Molecules!
We are fortunate to welcome Frauke Weidlich from Armido Studer's lab at the University of Muenster!
Congratulations to Harry, Diego and our collaborators from the Tantillo and Schofield labs for the publication of their recent work on the Synthesis and Application of Constrained Amidoboronic Acids Using Amphoteric Boron-Containing Building Blocks in the Journal of Organic Chemistry!
Congratulations to Tim for the completion of his M.Sc. thesis titled Conformational Analysis of Rotationally Restricted Macrocyclic Peptides !
A very warm welcome to our lab's first year graduate students Chelsey (B.Sc. UBC Okanagan), Nick (B.Sc. McMaster University), and Matthew (B.Sc. and M.Sc. University of Waterloo)!
Congratulations to Vincent, Tien and Alina for the publication of their review on the toic of Interruted reactions in chemical synthesis in Nature Reviews Chemistry!
Congratulations to Tien, Alina for the publication of Synthesis of Borylated Hydrazino Acid Derivatives in the Synthesis special issue dedicated to Prof. Sarah Reisman!
Congratulations to Harry, Diego and Katherine on the recent publication of their work on the Synthesis of Fluorinated Aminoalkylboronic Acids from Amphoteric α-Boryl Aldehydes in Angewandte Chemie!
Congratulations to Alina, Aleksandra, Tien and Martynas for the publication of their work on Acylboronates in Polarity-Reversed Generation of Acyl Palladium(II) Intermediates in Organic Letters!
Our most recent JACS article has been highlighted in Spotlights on Recent JACS Publications!
Congratulations to Shinya, Sean and Solomon for their publication on Two-Dimensional Barriers for Probing Conformational Shifts in Macrocycles in Journal of the American Chemical Society!
Congratulations to Aleks and Chirag for the publication of their perspective on Acyl Metalloids: Conformity and Deviation from Carbonyl Reactivity in Chemical Science!
Our most recent Nature Chemistry manuscript was featured as the cover for the March issue! A big thank you to artist Ella Marushchenko!
Congratulations to Diego, Solomon, Anastasia, Yury, Timothy and Gabe for the publication of their work on Illuminating the dark conformational space of macrocycles using dominant rotors in Nature Chemistry!
Andrei's invited opinion article on Space, energy and synthetic half-reactions has been published in Chemistry World!
We wish to welcome our new postdoctoral fellow George Saunders (PhD University of Warwick)!
Congratulations to Sherif, Tien, Stephanie, Marty and collaborators for their most recent publication on Oxidative Rearrangement of MIDA (N-Methyliminodiacetic Acid) Boronates: Mechanistic Insights and Synthetic Applications!
Congratulations to Sean and Solomon for the publication of their work on Amidine Functionality As a Conformational Probe of Cyclic Peptides in Organic Letters!
Congratulations to Tien, Alina and Aleks for the publication of the work on Carboxyboronate as a Versatile in situ CO surrogate in Palladium-Catalyzed Carbonylative Transformations in Angewandte Chemie!
Welcome to our new graduate student Alaeddeen Al-Toum (McMaster University)!
Have a look at Andrei's perspective article on Synthetic Half-Reactions out in Chemical Science!
Have a look at Frank, Tien and Shinya A.'s publication on the Synthesis of α-Bromoacetyl MIDA Boronate in Organic Syntheses!
Congratulations to our summer undergraduate NSERC student Seamus Corlett for earning an award at the department's annual summer poster session!
Congratulations to Dr. Aleksandra Holownia for defending her PhD thesis! The title of her thesis is Investigating the Synthesis and Reactivity of Boron Carbonyl Compounds. Aleksandra will joining the Process Chemistry group at AbbVie in Chicago!
Please join us in congratulating Diego (PhD '19) for winning the 2020 Chair's Gold Medal! The title of his thesis is Identification of novel structural motifs for mining the conformational space of boron- and peptide-based molecules.
Congratulations to Andrei on his recent appointment as a Tier 1 Canada Research Chair in Medicine by Design! "This CRC funding will allow my lab to understand how to force a wide range of chemical structures into unusual, yet stable, conformations," says Yudin. "We will apply the knowledge of the emerging dark space in our effort to generate new bioactive forms of chemical structures and understand how they interact with proteins and other biomolecules."
Check out Chirag, Diego and Timur's work on Grafting bis(heterocycle) motifs into ring structures in European Journal of Organic Chemistry!
Check out Yury and Chirag's work on Boramidine: A Versatile Structural Motif for the Design of Fluorescent Heterocycles in collaboration with the Seferos and Aspuru-Guzik group, published now in Journal of the American Chemical Society!
Check out Andrei's essay on discoverability in science posted on ChemRxiv!
Congratulations to Dr. Joanne Tan for successfully defending her PhD thesis!
Congratulations to Dr. Diego Diaz for successfully defending his PhD thesis!Diego is pursuing research as an NSERC postdoctoral fellow in the lab of Professor Eric Jacobsen at Harvard University.
Congratulations to Dr. Sherif Kaldas for successfully defending his PhD thesis! Sherif will be pursuing as postdoctoral fellow at RWTH Aachen University with Prof. Franziska Schoenebeck.
Welcome to our new graduate students Alina (University of Toronto), Martynas (University of Toronto Mississauga) and Timothy (University of Guelph) as well as our new visiting student Fiona (Johannes Gutenberg-University Mainz)!
Check out Solomon, Sean and Diego's recent Focus Review on Conformational Control of Macrocycles by Remote Structural Modification out now in Chemical Reviews!
Check out Aleks and Tien's work on Carboxy-MIDA-boronate: a new versatile C1 building block published in Angewandte Chemie!
Check out Aki and Sherif's recent work on using the Petasis borono-Mannich reaction to access conformationnaly stable peptide macrocycles published in Chemical Communications!
Check out Joanne's new paper on boron-based peptidomimetics inhibitors out now in Journal of Medicinal Chemistry!
Congratulations to Andrei for being awarded a Killam Research Fellowship Prize!
Congratulations to Andrei for winning the 2019 R.U. Lemieux Award!
From December 1 2018, Andrei will serve as an Associate Editor of Chemical Science!
Check out Joanne’s review on borylated reagents for multicomponent processes in Drug Discovery Today: Technologies!